2021 is about 3 themes for me: Clarity, Value, and Flow

Clarity of clear outcomes and end-to-end visibility
Value of a customer focus, and value stream thinking
Flow of work, info, communications, and value - forgetting the org chart and living in the value streams

In a nutshell, understanding that your org is not your org chart, it's a collection of value streams first and foremost, and once you start thinking that way everything starts to flow together in the right direction.